Dimethylsulfoxide (DMSO)

What is DMSO, how is it used on horses, and what are the risks?


Dimethylsulfoxide (DMSO), a byproduct of the chemical solvent industry, was approved by the FDA to treat musculoskeletal disorders in horses and dogs more than 30 years ago.

Today DMSO is commonly used by horse owners and veterinarians to relieve swelling and inflammation. When used topically, it causes moderate to intense heat—a benefit in treating old injuries that are still swollen but firm and cold to the touch.

However, many veterinarians argue that DMSO produces exactly the opposite effect you want when treating a recent injury. Initial treatment for bumps and traumas that are hot and swollen to the touch is cold therapy; hosing a swollen joint or ligament with cold water and icing the area is standard primary emergency care. Putting DMSO on a “fresh” injury increases the heat in that area and can actually increase inflammation.

Always wear rubber gloves when using DMSO, since it is rapidly absorbed by deep tissues—in humans and horses alike. This rapid absorption can be beneficial, especially when DMSO is mixed with other veterinarian-approved topical substances—like antibiotics and anti-inflammatory drugs.

Always check with your vet before using DMSO—mixing the solvent with some substances can be very dangerous. Also, DMSO acts as a carrier agent, so anything on your horse’s skin (i.e. dirt and bacteria) will also be carried into the bloodstream.

DMSO can be irritating to horses, and some will stamp their feet and even rub and chew treated areas. DMSO should not be used on an open wound.

Back to Liniments and Poultices for Sore Horses


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