New pain killer for horses suffering from arthritis gets FDA approval


Equioxx was approved as a safe NSAID to use on horsesEquioxx paste, a nonsteroidal anti-inflammatory drug (NSAID) for use in horses, is now available to help relieve joint pain and inflammation associated with osteoarthritis.

“In trails, Equioxx had impressive results reducing pain and inflammation. It is a long-awaited NSAID paste designed specifically for horses that has an excellent safety profile,” says Merial executive director, pharmaceutical R&D projects, Peter Hanson, DVM, PhD, Dipl ACVS.

Recently there has been growing concern about the safety of long-term use of NSAIDs, such as bute and others. According to a report from Merial, a targeted study was conducted that evaluated safety and side effects of firocoxib, the active ingredient in Equioxx. The study involved 30 horses of various breeds and sizes. Horses receiving the normal recommended dose (once daily) of firocoxib did not experience any treatment-related side effects. Findings also showed that after one dose of Equioxx, the drug remained in the horses’ bloodstreams over a long time period, suggesting that one treatment is effective for 24 hours. Based on study results, 84 percent of horses treated with Equioxx showed improvement.

Equioxx has not been tested in horses less than 1 year of age, or in breeding horses, or pregnant or lactating mares. Use with other NSAIDs or corticosteroids should be avoided.
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  1. I think its really interesting, we started our 14 yr old qh on Equioxx. It seems like it helped her alot within 4 hrs.
    The Vet is checking with us every day to see if she is improving.

  2. I have been using this product for several months on a 29 year old gelding. It seems to work very well – however the cost is prohibitive. One can only hope that the cost will come down

  3. We used this on a 34 year old appaloosa, and it was a miracle – he is moving/feeling so much better than when on bute.Not sure what we do after the fourteen days?

  4. My mare horse,gets hives when giving bute.
    I have to give her antihistamine,with gastrix,so her stomach doesn’t suffer and of course,apple sauce mixture…and then I’ll give her the bute.
    My question is:will that new FDA approved pain killer give her hives?


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